Built in 1811, the Samuel Whitehorne House is a rare example of a Federal-style mansion. It features an elegant hipped roof, a classically inspired entry portico, and a formal garden. The interior is highlighted by a grand central hallway, hand-carved details, and a significant collection of 18th century American furniture.

Samuel Whitehorne Jr. (1779-1844) made a fortune in Newport through a variety of commercial enterprises, including rum distilling, banking, shipping, and likely slave trading. With the town's economy in shambles after the American Revolution, Whitehorne was one of the Newport's last great merchant princes.

Built on Thames Street and proudly facing the water, Whitehorne's house was to be a symbol of his prosperity. Unfortunately, after two of his ships were lost at sea, he went bankrupt. Sold at auction in 1843, his house was converted to shops and apartments and gradually deteriorated until it was purchased and restored by the Newport Restoration Foundation in 1969.